Model‐based simulation to support the approval of isatuximab alone or with dexamethasone for the treatment of relapsed/refractory multiple myeloma in Japanese patients

• 主要な著者: Hoai‐Thu Thai (著者), Kimiko Koiwai (著者), Yoshihisa Shitara (著者), Hirotaka Kazama (著者), Jean‐Baptiste Fau (著者), Dorothée Semiond (著者), Christine Veyrat‐Follet (著者)
• フォーマット: 図書
• 出版事項: Wiley, 2023-12-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Abstract This study aimed to support dosing regimen selection for isatuximab as a single agent or in combination with dexamethasone for Japanese patients with relapsed/refractory multiple myeloma (RRMM). A joint model characterizing the dynamics of serum M‐protein kinetics and its association with p...