Dietary ω-3 Fatty Acid Supplementation Improves Murine Sickle Cell Bone Disease and Reprograms Adipogenesis

• Autors principals: Maria Teresa Valenti (Autor), Alessandro Mattè (Autor), Enrica Federti (Autor), Mark Puder (Autor), Lorenzo Anez-Bustillos (Autor), Michela Deiana (Autor), Samuele Cheri (Autor), Arianna Minoia (Autor), Carlo Brugnara (Autor), Maria Luisa Di Paolo (Autor), Luca Dalle Carbonare (Autor), Lucia De Franceschi (Autor)
• Format: Llibre
• Publicat: MDPI AG, 2021-05-01T00:00:00Z.
• Matèries: article
• Accés en línia: Connect to this object online.

Sickle cell disease (SCD) is a genetic disorder of hemoglobin, leading to chronic hemolytic anemia and multiple organ damage. Among chronic organ complications, sickle cell bone disease (SBD) has a very high prevalence, resulting in long-term disability, chronic pain and fractures. Here, we evaluate...