Sal003 alleviated intervertebral disc degeneration by inhibiting apoptosis and extracellular matrix degradation through suppressing endoplasmic reticulum stress pathway in rats

• Главные авторы: Yan Chen (Автор), Baixing Li (Автор), Yue Xu (Автор), Tangjun Zhou (Автор), Changqing Zhao (Автор), Jie Zhao (Автор)
• Формат: ‌
• Опубликовано: Frontiers Media S.A., 2023-01-01T00:00:00Z.
• Предметы: article
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Apoptosis and extracellular matrix degradation of the nucleus pulposus are the main initiators of intervertebral disc degeneration (IVDD) and can be explained by endoplasmic reticulum (ER) stress. Thus, pharmacological therapy aimed at suppressing this pathway may be a promising approach for the man...