Antitumor Effect of Fluoxetine on Chronic Stress-Promoted Lung Cancer Growth via Suppressing Kynurenine Pathway and Enhancing Cellular Immunity

• Главные авторы: Zhen Yang (Автор), Zhuman Li (Автор), Zhijun Guo (Автор), Yu Ren (Автор), Ting Zhou (Автор), Zhijun Xiao (Автор), Jingjing Duan (Автор), Chuangchuang Han (Автор), Yuanchi Cheng (Автор), Feng Xu (Автор)
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• Опубликовано: Frontiers Media S.A., 2021-08-01T00:00:00Z.
• Предметы: article
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Background: Chronic stress promotes cancer growth. Antidepressant fluoxetine (FLX) is usually prescribed for cancer patients with comorbid depression. FLX displays inhibition on cancer cell proliferation, however, the in vivo activity has not been investigated.Methods: We explored the antitumor effe...