The gut microbiota as a modulator of innate immunity during melioidosis.

• Egile Nagusiak: Jacqueline M Lankelma (Egilea), Emma Birnie (Egilea), Tassili A F Weehuizen (Egilea), Brendon P Scicluna (Egilea), Clara Belzer (Egilea), Riekelt H Houtkooper (Egilea), Joris J T H Roelofs (Egilea), Alex F de Vos (Egilea), Tom van der Poll (Egilea), Andries E Budding (Egilea), W Joost Wiersinga (Egilea)
• Formatua: Liburua
• Argitaratua: Public Library of Science (PLoS), 2017-04-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

BACKGROUND:Melioidosis, caused by the Gram-negative bacterium Burkholderia pseudomallei, is an emerging cause of pneumonia-derived sepsis in the tropics. The gut microbiota supports local mucosal immunity and is increasingly recognized as a protective mediator in host defenses against systemic infec...