In Silico Antiprotozoal Evaluation of 1,4-Naphthoquinone Derivatives against Chagas and Leishmaniasis Diseases Using QSAR, Molecular Docking, and ADME Approaches

• Main Authors: Lina S. Prieto Cárdenas (Author), Karen A. Arias Soler (Author), Diana L. Nossa González (Author), Wilson E. Rozo Núñez (Author), Agobardo Cárdenas-Chaparro (Author), Pablo R. Duchowicz (Author), Jovanny A. Gómez Castaño (Author)
• Format: Book
• Published: MDPI AG, 2022-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Chagas and leishmaniasis are two neglected diseases considered as public health problems worldwide, for which there is no effective, low-cost, and low-toxicity treatment for the host. Naphthoquinones are ligands with redox properties involved in oxidative biological processes with a wide variety of...