In Silico Antiprotozoal Evaluation of 1,4-Naphthoquinone Derivatives against Chagas and Leishmaniasis Diseases Using QSAR, Molecular Docking, and ADME Approaches

• Prif Awduron: Lina S. Prieto Cárdenas (Awdur), Karen A. Arias Soler (Awdur), Diana L. Nossa González (Awdur), Wilson E. Rozo Núñez (Awdur), Agobardo Cárdenas-Chaparro (Awdur), Pablo R. Duchowicz (Awdur), Jovanny A. Gómez Castaño (Awdur)
• Fformat: Llyfr
• Cyhoeddwyd: MDPI AG, 2022-05-01T00:00:00Z.
• Pynciau: article
• Mynediad Ar-lein: Connect to this object online.

Chagas and leishmaniasis are two neglected diseases considered as public health problems worldwide, for which there is no effective, low-cost, and low-toxicity treatment for the host. Naphthoquinones are ligands with redox properties involved in oxidative biological processes with a wide variety of...