In Silico Antiprotozoal Evaluation of 1,4-Naphthoquinone Derivatives against Chagas and Leishmaniasis Diseases Using QSAR, Molecular Docking, and ADME Approaches

• Autori principali: Lina S. Prieto Cárdenas (Autore), Karen A. Arias Soler (Autore), Diana L. Nossa González (Autore), Wilson E. Rozo Núñez (Autore), Agobardo Cárdenas-Chaparro (Autore), Pablo R. Duchowicz (Autore), Jovanny A. Gómez Castaño (Autore)
• Natura: Libro
• Pubblicazione: MDPI AG, 2022-05-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Chagas and leishmaniasis are two neglected diseases considered as public health problems worldwide, for which there is no effective, low-cost, and low-toxicity treatment for the host. Naphthoquinones are ligands with redox properties involved in oxidative biological processes with a wide variety of...