Benzylamides and piperazinoarylamides of ibuprofen as fatty acid amide hydrolase inhibitors

• Main Authors: Alessandro Deplano (Author), Mariateresa Cipriano (Author), Federica Moraca (Author), Ettore Novellino (Author), Bruno Catalanotti (Author), Christopher J. Fowler (Author), Valentina Onnis (Author)
• Format: Book
• Published: Taylor & Francis Group, 2019-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Fatty Acid Amide Hydrolase (FAAH) is a serine hydrolase that plays a key role in controlling endogenous levels of endocannabinoids. FAAH inhibition is considered a powerful approach to enhance the endocannabinoid signalling, and therefore it has been largely studied as a potential target for the tre...