Benzylamides and piperazinoarylamides of ibuprofen as fatty acid amide hydrolase inhibitors

• Hlavní autoři: Alessandro Deplano (Autor), Mariateresa Cipriano (Autor), Federica Moraca (Autor), Ettore Novellino (Autor), Bruno Catalanotti (Autor), Christopher J. Fowler (Autor), Valentina Onnis (Autor)
• Médium: Kniha
• Vydáno: Taylor & Francis Group, 2019-01-01T00:00:00Z.
• Témata: article
• On-line přístup: Connect to this object online.

Fatty Acid Amide Hydrolase (FAAH) is a serine hydrolase that plays a key role in controlling endogenous levels of endocannabinoids. FAAH inhibition is considered a powerful approach to enhance the endocannabinoid signalling, and therefore it has been largely studied as a potential target for the tre...