Effects of Anti-TNFα Treatment on Mucosal Expression of IL-17A, IL-21, and IL-22 and Cytokine-Producing T Cell Subsets in Crohn's Disease

• Egile Nagusiak: Anders Dige (Egilea), Maria K. Magnusson (Egilea), Claus Uhrenholt (Egilea), Tue Kruse Rasmussen (Egilea), Tue Kragstrup (Egilea), Lena Öhman (Egilea), Jens Dahlerup (Egilea), Jørgen Agnholt (Egilea)
• Formatua: Liburua
• Argitaratua: Hindawi Limited, 2018-01-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

T helper 17 (Th17) cells produce interleukin (IL) 17-A. In addition, Th17 cells produce IL-21 and IL-22. Th17 cells have a disease-promoting role in Crohn's disease (CD). We investigated the effects of anti-TNFα treatment on mucosal gene expression (qPCR) of IL-17A, IL-21, and IL-22 as well as...