Effects of Anti-TNFα Treatment on Mucosal Expression of IL-17A, IL-21, and IL-22 and Cytokine-Producing T Cell Subsets in Crohn's Disease

• Główni autorzy: Anders Dige (Autor), Maria K. Magnusson (Autor), Claus Uhrenholt (Autor), Tue Kruse Rasmussen (Autor), Tue Kragstrup (Autor), Lena Öhman (Autor), Jens Dahlerup (Autor), Jørgen Agnholt (Autor)
• Format: Książka
• Wydane: Hindawi Limited, 2018-01-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

T helper 17 (Th17) cells produce interleukin (IL) 17-A. In addition, Th17 cells produce IL-21 and IL-22. Th17 cells have a disease-promoting role in Crohn's disease (CD). We investigated the effects of anti-TNFα treatment on mucosal gene expression (qPCR) of IL-17A, IL-21, and IL-22 as well as...