Heme in pathophysiology: a matter of scavenging, metabolism and trafficking across cell membranes

• Asıl Yazarlar: Deborah eChiabrando (Yazar), Francesca eVinchi (Yazar), Veronica eFiorito (Yazar), Sonia eMercurio (Yazar), Emanuela eTolosano (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Frontiers Media S.A., 2014-04-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Heme (iron-protoporphyrin IX) is an essential co-factor involved in multiple biological processes: oxygen transport and storage, electron transfer, drug and steroid metabolism, signal transduction, and micro RNA processing. However, excess free-heme is highly toxic due to its ability to promote oxid...