β-Tocotrienol Decreases PDGF-BB-Induced Proliferation and Migration of Human Airway Smooth Muscle Cells by Inhibiting RhoA and Reducing ROS Production

• Hoofdauteurs: Aditya Sri Listyoko (Auteur), Ryota Okazaki (Auteur), Tomoya Harada (Auteur), Miki Takata (Auteur), Masato Morita (Auteur), Hiroki Ishikawa (Auteur), Yoshihiro Funaki (Auteur), Akira Yamasaki (Auteur)
• Formaat: Boek
• Gepubliceerd in: MDPI AG, 2024-05-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Background: Tocotrienols exhibit antioxidant and anti-inflammatory activities. RhoA, a small GTPase protein, plays a crucial role in regulating contractility in airway smooth muscle (ASM). Previous studies have demonstrated that γ-tocotrienols reduce ASM proliferation and migration by inhibiting the...