β-Tocotrienol Decreases PDGF-BB-Induced Proliferation and Migration of Human Airway Smooth Muscle Cells by Inhibiting RhoA and Reducing ROS Production

• Váldodahkkit: Aditya Sri Listyoko (Dahkki), Ryota Okazaki (Dahkki), Tomoya Harada (Dahkki), Miki Takata (Dahkki), Masato Morita (Dahkki), Hiroki Ishikawa (Dahkki), Yoshihiro Funaki (Dahkki), Akira Yamasaki (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: MDPI AG, 2024-05-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

Background: Tocotrienols exhibit antioxidant and anti-inflammatory activities. RhoA, a small GTPase protein, plays a crucial role in regulating contractility in airway smooth muscle (ASM). Previous studies have demonstrated that γ-tocotrienols reduce ASM proliferation and migration by inhibiting the...