The importance of targeting signalling mechanisms of the SLC39A family of zinc transporters to inhibit endocrine resistant breast cancer

The importance of targeting signalling mechanisms of the SLC39A family of zinc transporters to inhibit endocrine resistant breast cancer

Aim: Zinc is a key secondary messenger that can regulate multiple signalling pathways within cancer cells, thus its levels need to be strictly controlled. The Zrt, Irt-like protein (ZIP, SLC39A) family of zinc transporters increase cytosolic zinc from either extracellular or intracellular stores. Th...

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Main Authors: Samuel Jones (Author), Georgia Farr (Author), Thirayost Nimmanon (Author), Silvia Ziliotto (Author), Julia M.W. Gee (Author), Kathryn M. Taylor (Author)
Format: Book
Published: Open Exploration Publishing Inc., 2022-04-01T00:00:00Z.
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3rd Floor Main Library

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