Serum Metabolomic Profiling Reveals the Amelioration Effect of Methotrexate on Imiquimod-Induced Psoriasis in Mouse

• Main Authors: Jiaxin Zong (Author), Jieyi Cheng (Author), Yuanfeng Fu (Author), Jing Song (Author), Weisong Pan (Author), Li Yang (Author), Ting Zhang (Author), Mingmei Zhou (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background:The imiquimod (IMQ)-induced psoriasis mouse model has been used as a model for pathogenic mechanism research, and methotrexate (MTX) is widely employed to treat various clinical manifestations of psoriasis. We explored the underlying pathogenesis of psoriasis and the treatment mechanism o...