Serum Metabolomic Profiling Reveals the Amelioration Effect of Methotrexate on Imiquimod-Induced Psoriasis in Mouse

• Autores principales: Jiaxin Zong (Autor), Jieyi Cheng (Autor), Yuanfeng Fu (Autor), Jing Song (Autor), Weisong Pan (Autor), Li Yang (Autor), Ting Zhang (Autor), Mingmei Zhou (Autor)
• Formato: Libro
• Publicado: Frontiers Media S.A., 2020-11-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

Background:The imiquimod (IMQ)-induced psoriasis mouse model has been used as a model for pathogenic mechanism research, and methotrexate (MTX) is widely employed to treat various clinical manifestations of psoriasis. We explored the underlying pathogenesis of psoriasis and the treatment mechanism o...