Inflammation as a Possible Trigger for Mitoxantrone-Induced Cardiotoxicity: An In Vivo Study in Adult and Infant Mice

• मुख्य लेखकों: Ana Reis-Mendes (लेखक), José Luís Dores-Sousa (लेखक), Ana Isabel Padrão (लेखक), Margarida Duarte-Araújo (लेखक), José Alberto Duarte (लेखक), Vítor Seabra (लेखक), Salomé Gonçalves-Monteiro (लेखक), Fernando Remião (लेखक), Félix Carvalho (लेखक), Emília Sousa (लेखक), Maria Lourdes Bastos (लेखक), Vera Marisa Costa (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2021-05-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Mitoxantrone (MTX) is a pharmaceutical drug used in the treatment of several cancers and refractory multiple sclerosis (MS). Despite its therapeutic value, adverse effects may be severe, namely the frequently reported cardiotoxicity, whose mechanisms need further research. This work aimed to assess...