Magnetically Assisted Drug Delivery of Topical Eye Drops Maintains Retinal Function In Vivo in Mice

• المؤلفون الرئيسيون: Marco Bassetto (مؤلف), Daniel Ajoy (مؤلف), Florent Poulhes (مؤلف), Cathy Obringer (مؤلف), Aurelie Walter (مؤلف), Nadia Messadeq (مؤلف), Amir Sadeghi (مؤلف), Jooseppi Puranen (مؤلف), Marika Ruponen (مؤلف), Mikko Kettunen (مؤلف), Elisa Toropainen (مؤلف), Arto Urtti (مؤلف), Hélène Dollfus (مؤلف), Olivier Zelphati (مؤلف), Vincent Marion (مؤلف)
• التنسيق: كتاب
• منشور في: MDPI AG, 2021-10-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

Barded-Biedl syndrome (BBS) is a rare genetic disorder with an unmet medical need for retinal degeneration. Small-molecule drugs were previously identified to slow down the apoptosis of photoreceptors in BBS mouse models. Clinical translation was not practical due to the necessity of repetitive inva...