Time course of altered sensitivity to inhibitory and excitatory agonist responses in the longitudinal muscle-myenteric plexus and analgesia in the guinea pig after chronic morphine treatment

• 主要な著者: Dane M Barrett (著者), Hercules Tarambirwa Maguma (著者), David A Taylor (著者)
• フォーマット: 図書
• 出版事項: Frontiers Media S.A., 2012-01-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Tolerance that develops after chronic morphine exposure has been proposed to be an adaptive response that develops and decays over a defined time course. The present study examined the development of tolerance to the acute hypothermic and analgesic effects of morphine and correlated the time course...