Time course of altered sensitivity to inhibitory and excitatory agonist responses in the longitudinal muscle-myenteric plexus and analgesia in the guinea pig after chronic morphine treatment

• मुख्य लेखकों: Dane M Barrett (लेखक), Hercules Tarambirwa Maguma (लेखक), David A Taylor (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Frontiers Media S.A., 2012-01-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Tolerance that develops after chronic morphine exposure has been proposed to be an adaptive response that develops and decays over a defined time course. The present study examined the development of tolerance to the acute hypothermic and analgesic effects of morphine and correlated the time course...