cCPE Fusion Proteins as Molecular Probes to Detect Claudins and Tight Junction Dysregulation in Gastrointestinal Cell Lines, Tissue Explants and Patient-Derived Organoids
Claudins regulate paracellular permeability, contribute to epithelial polarization and are dysregulated during inflammation and carcinogenesis. Variants of the claudin-binding domain of <i>Clostridium perfringens</i> enterotoxin (cCPE) are highly sensitive protein ligands for generic det...
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Main Authors: | Ayk Waldow (Author), Laura-Sophie Beier (Author), Janine Arndt (Author), Simon Schallenberg (Author), Claudia Vollbrecht (Author), Philip Bischoff (Author), Martí Farrera-Sal (Author), Florian N. Loch (Author), Christian Bojarski (Author), Michael Schumann (Author), Lars Winkler (Author), Carsten Kamphues (Author), Lukas Ehlen (Author), Jörg Piontek (Author) |
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Format: | Book |
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MDPI AG,
2023-07-01T00:00:00Z.
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