Enhancing oral bioavailability of andrographolide using solubilizing agents and bioenhancer: comparative pharmacokinetics of Andrographis paniculata formulations in beagle dogs

• Hauptverfasser: Phanit Songvut (Verfasst von), Tussapon Boonyarattanasoonthorn (Verfasst von), Nitra Nuengchamnong (Verfasst von), Thammaporn Junsai (Verfasst von), Teetat Kongratanapasert (Verfasst von), Kittitach Supannapan (Verfasst von), Phisit Khemawoot (Verfasst von)
• Format: Buch
• Veröffentlicht: Taylor & Francis Group, 2024-12-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

AbstractContext The therapeutic potential of andrographolide is hindered by its poor oral bioavailability and unpredictable pharmacokinetics, primarily due to its limited water solubility.Objective This work aimed to enhance the solubility and pharmacokinetics of andrographolide, a bioactive compoun...