Blockade of the Notch1/Jagged1 pathway in Kupffer cells aggravates ischemia-reperfusion injury of orthotopic liver transplantation in mice

• Asıl Yazarlar: He Bai (Yazar), Jian Wen (Yazar), Jian-Ping Gong (Yazar), Hao Wu (Yazar), Fang-Chao Yuan (Yazar), Ding Cao (Yazar), Ya-Kun Wu (Yazar), Xing Lai (Yazar), Meng-Hao Wang (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Taylor & Francis Group, 2019-05-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Liver ischemia-reperfusion injury (IRI) represents a risk factor for early graft dysfunction and an obstacle to expanding donor pool in orthotopic liver transplantation (OLT). Kupffer cells (KCs) are the largest antigen-presenting cell (APC) group and the primary modulators of inflammation in liver...