NGS-based accurate and efficient detection of circulating cell-free mitochondrial DNA in cancer patients

• Asıl Yazarlar: Yang Liu (Yazar), Kaixiang Zhou (Yazar), Shanshan Guo (Yazar), Yang Wang (Yazar), Xiaoying Ji (Yazar), Qing Yuan (Yazar), Liping Su (Yazar), Xu Guo (Yazar), Xiwen Gu (Yazar), Jinliang Xing (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Elsevier, 2021-03-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Mitochondrial DNA (mtDNA) mutations are closely implicated in the pathogenesis of multiple cancers, making circulating cell-free mtDNA (ccf-mtDNA) as a potential non-invasive tumor biomarker. However, an effective approach to comprehensively profile ccf-mtDNA mutations is still lacking. In this stud...