NGS-based accurate and efficient detection of circulating cell-free mitochondrial DNA in cancer patients
Mitochondrial DNA (mtDNA) mutations are closely implicated in the pathogenesis of multiple cancers, making circulating cell-free mtDNA (ccf-mtDNA) as a potential non-invasive tumor biomarker. However, an effective approach to comprehensively profile ccf-mtDNA mutations is still lacking. In this stud...
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Elsevier,
2021-03-01T00:00:00Z.
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