PKA phosphorylation of Cav1.2 channel modulates the interaction of calmodulin with the C terminal tail of the channel

Activity of cardiac Cav1.2 channels is enhanced by cyclic AMP-PKA signaling. In this study, we studied the effects of PKA phosphorylation on the binding of calmodulin to the fragment peptide of the proximal C-terminal tail of α1C subunit (CT1, a.a. 1509-1789 of guinea-pig). In the pull-down assay, i...

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Main Authors: Ming Lei (Author), Jianjun Xu (Author), Qinghua Gao (Author), Etsuko Minobe (Author), Masaki Kameyama (Author), Liying Hao (Author)
Format: Book
Published: Elsevier, 2018-06-01T00:00:00Z.
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