Glasdegib Dimaleate: Synthesis, Characterization and Comparison of Its Properties with Monomaleate Analogue

Glasdegib Dimaleate: Synthesis, Characterization and Comparison of Its Properties with Monomaleate Analogue

Glasdegib is a recently approved drug for the treatment of acute myeloid leukemia. It is formulated and marketed in monomaleate salt form. In our investigation, we were able to prepare a glasdegib dimaleate form, which could, in theory, exist in double-salt form or as a mixture of salt and co-crysta...

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Main Authors: Boris Peklar (Author), Franc Perdih (Author), Damjan Makuc (Author), Janez Plavec (Author), Jérôme Cluzeau (Author), Zoran Kitanovski (Author), Zdenko Časar (Author)
Format: Book
Published: MDPI AG, 2022-08-01T00:00:00Z.
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