Inhibition of Autophagy In Vivo Extends Methamphetamine Toxicity to Mesencephalic Cell Bodies

• Автори: Michela Ferrucci (Автор), Francesca Biagioni (Автор), Carla L. Busceti (Автор), Chiara Vidoni (Автор), Roberta Castino (Автор), Ciro Isidoro (Автор), Larisa Ryskalin (Автор), Alessandro Frati (Автор), Stefano Puglisi-Allegra (Автор), Francesco Fornai (Автор)
• Формат: Книга
• Опубліковано: MDPI AG, 2021-09-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

Methamphetamine (METH) is a widely abused psychostimulant and a stress-inducing compound, which leads to neurotoxicity for nigrostriatal dopamine (DA) terminals in rodents and primates including humans. In vitro studies indicate that autophagy is a strong modulator of METH toxicity. In detail, suppr...