Atorvastatin and Conditioned Media from Atorvastatin-Treated Human Hematopoietic Stem/Progenitor-Derived Cells Show Proangiogenic Activity In Vitro but Not In Vivo

• Главные авторы: Witold N. Nowak (Автор), Hevidar Taha (Автор), Joanna Markiewicz (Автор), Neli Kachamakova-Trojanowska (Автор), Jacek Stępniewski (Автор), Damian Klóska (Автор), Urszula Florczyk-Soluch (Автор), Rafał Niżankowski (Автор), Marzena Frołow (Автор), Zbigniew Walter (Автор), Józef Dulak (Автор), Alicja Józkowicz (Автор)
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• Опубликовано: Hindawi Limited, 2019-01-01T00:00:00Z.
• Предметы: article
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Myeloid angiogenic cells (MAC) derive from hematopoietic stem/progenitor cells (HSPCs) that are mobilized from the bone marrow. They home to sites of neovascularization and contribute to angiogenesis by production of paracrine factors. The number and function of proangiogenic cells are impaired in p...