CaMKII-Dependent Contractile Dysfunction and Pro-Arrhythmic Activity in a Mouse Model of Obstructive Sleep Apnea

• Hoofdauteurs: Philipp Hegner (Auteur), Simon Lebek (Auteur), Benedikt Schaner (Auteur), Florian Ofner (Auteur), Mathias Gugg (Auteur), Lars Siegfried Maier (Auteur), Michael Arzt (Auteur), Stefan Wagner (Auteur)
• Formaat: Boek
• Gepubliceerd in: MDPI AG, 2023-01-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Left ventricular contractile dysfunction and arrhythmias frequently occur in patients with sleep-disordered breathing (SDB). The CaMKII-dependent dysregulation of cellular Ca homeostasis has recently been described in SDB patients, but these studies only partly explain the mechanism and are limited...