CaMKII-Dependent Contractile Dysfunction and Pro-Arrhythmic Activity in a Mouse Model of Obstructive Sleep Apnea

• मुख्य लेखकों: Philipp Hegner (लेखक), Simon Lebek (लेखक), Benedikt Schaner (लेखक), Florian Ofner (लेखक), Mathias Gugg (लेखक), Lars Siegfried Maier (लेखक), Michael Arzt (लेखक), Stefan Wagner (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2023-01-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Left ventricular contractile dysfunction and arrhythmias frequently occur in patients with sleep-disordered breathing (SDB). The CaMKII-dependent dysregulation of cellular Ca homeostasis has recently been described in SDB patients, but these studies only partly explain the mechanism and are limited...