Butorphanol: Effects of a Prototypical Agonist-Antagonist Analgesic on κ-Opioid Receptors

• Main Authors: Stephen Commiskey (Author), Lir-Wan Fan (Author), Ing K. Ho (Author), Rob W. Rockhold (Author)
• Formato: Livro
• Publicado em: Elsevier, 2005-01-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

The opioid analgesic, butorphanol (17-cyclobutylmethyl-3,14-dihydroxymorphinan) tartrate is a prototypical agonist-antagonist opioid analgesic agent whose potential for abuse has been the cause of litigation in the United States. With a published affinity for opioid receptors in vitro of 1:4:25 (µ:δ...