Redox-responsive biocompatible nanocarriers based on novel heparosan polysaccharides for intracellular anticancer drug delivery

• मुख्य लेखकों: Lipeng Qiu (लेखक), Lu Ge (लेखक), Miaomiao Long (लेखक), Jing Mao (लेखक), Kamel S. Ahmed (लेखक), Xiaotian Shan (लेखक), Huijie Zhang (लेखक), Li Qin (लेखक), Guozhong Lv (लेखक), Jinghua Chen (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Elsevier, 2020-01-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Heparosan is a natural precursor of heparin biosynthesis in mammals. It is stable in blood circulation but can be degraded in lysosomes, showing good biocompatibility and long circulation features. So heparosan can be designed as anticancer drug carriers to increase tumor selectivity and improve the...