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A cheminformatics and network pharmacology approach to elucidate the mechanism of action of Mycobacterium tuberculosis γ-carbonic anhydrase inhibitors

BackgroundMycobacterium tuberculosis (Mtb) carbonic anhydrases (CAs) are critical enzymes that regulate pH by converting CO2 to HCO3−, essential for Mtb's survival in acidic environments. Inhibiting γ-CAs presents a potential target for novel antituberculosis drugs with unique mechanisms of act...

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Main Authors:	Ajay Manaithiya (Author), Ratul Bhowmik (Author), Kunal Bhattacharya (Author), Rajarshi Ray (Author), Sagar Singh Shyamal (Author), Fabrizio Carta (Author), Claudiu T. Supuran (Author), Seppo Parkkila (Author), Ashok Aspatwar (Author)
Format:	Book
Published:	Frontiers Media S.A., 2024-09-01T00:00:00Z.
Subjects:	article
Online Access:	Connect to this object online.
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