Cover Image

The Effect of Simvastatin on Gut Microbiota and Lipid Metabolism in Hyperlipidemic Rats Induced by a High-Fat Diet

The objective of this study was to investigate the effects of simvastatin (SIM) on lipid metabolism disorders and gut microbiota in high-fat diet-induced hyperlipidemic rats. The obtained results revealed that feeding rats with SIM (20 mg/kg/day) significantly decreased serum lipid level and inhibit...

Full description

Saved in:

Bibliographic Details
Main Authors:	Qing Zhang (Author), Xiaoyun Fan (Author), Rui Ye (Author), Yuzhong Hu (Author), Tingting Zheng (Author), Rui Shi (Author), Wenjian Cheng (Author), Xucong Lv (Author), Lijiao Chen (Author), Peng Liang (Author)
Format:	Book
Published:	Frontiers Media S.A., 2020-04-01T00:00:00Z.
Subjects:	article
Online Access:	Connect to this object online.
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Asparagus cochinchinensis alleviates disturbances of lipid metabolism and gut microbiota in high-fat diet-induced obesity mice
by: Shiyue Luo, et al.
Published: (2022)

Gut microbiota and metabolomics unveil the mechanisms of Lomatogonium rotatum in ameliorating visceral fat and serum lipids in high-fat diet-induced obese mice
by: Xiaoping Ji, et al.
Published: (2024)

Influence of anti-hyperlipidemic activity by co-administration of polyamines and rutin with simvastatin
by: Rajesh R Patil, et al.
Published: (2023)

Dietary fat and gut microbiota interactions determine diet-induced obesity in mice
by: Raphaela Kübeck, et al.
Published: (2016)

Antihyperlipidemic effects of apple peel extract in high-fat diet-induced hyperlipidemic rats
by: Retno Susilowati, et al.
Published: (2020)

Diosgenin Ameliorates Non-alcoholic Fatty Liver Disease by Modulating the Gut Microbiota and Related Lipid/Amino Acid Metabolism in High Fat Diet-Fed Rats
by: Yuan Zhou, et al.
Published: (2022)

Polydextrose Alleviates Adipose Tissue Inflammation and Modulates the Gut Microbiota in High-Fat Diet-Fed Mice
by: Qiuyue Hu, et al.
Published: (2022)

Influence of diet on the gut microbiota
by: Justyna Dąbrowska, et al.
Published: (2020)

Anti-oxidant and anti-hyperlipidemic activity of Hemidesmus indicus in rats fed with high-fat diet
by: Suganya Venkateshan, et al.
Published: (2016)

Effect of methanol extract of Salviae miltiorrhizae Radix in high-fat diet-induced hyperlipidemic mice
by: Chiyeon Lim, et al.
Published: (2017)

Simvastatin ameliorates oxidative stress levels in HepG2 cells and hyperlipidemic rats
by: Kanika Verma, et al.
Published: (2022)

Effects of Xylooligosaccharides on Lipid Metabolism, Inflammation, and Gut Microbiota in C57BL/6J Mice Fed a High-Fat Diet
by: Fang Li, et al.
Published: (2021)

Single and combined effect of vinyl chloride monomer and high-fat diet on gut microbiota in mice
by: Yan HAO, et al.
Published: (2022)

Naoxintong Capsule Alternates Gut Microbiota and Prevents Hyperlipidemia in High-Fat-Diet Fed Rats
by: Yihang Lu, et al.
Published: (2022)

Glucosamine Ameliorates Symptoms of High-Fat Diet-Fed Mice by Reversing Imbalanced Gut Microbiota
by: Xubing Yuan, et al.
Published: (2021)

Antihyperlipidemic and antiatherogenic activities of Terminalia pallida Linn. fruits in high fat diet-induced hyperlipidemic rats
by: M T Sampathkumar, et al.
Published: (2011)

Inulin ameliorates metabolic syndrome in high-fat diet-fed mice by regulating gut microbiota and bile acid excretion
by: Shaoxiong Huang, et al.
Published: (2023)

Effect of Simvastatin on Spatial Memory of Rats Receiving a High-Fat Diet
by: Asra Margdari, et al.
Published: (2017)

Effect of Simvastatin on Spatial Memory of Rats Receiving a High-Fat Diet
by: Asra Margdari, et al.
Published: (2017)

Gut Microbiota, the Ketogenic Diet and Epilepsy
by: Egidio Spinelli, et al.
Published: (2018)

Effects of voluntary exercise on plasma and urinary metabolites and gut microbiota in mice fed with high-fat-diet
by: Chihiro Watanabe, et al.
Published: (2020)

Altered gut microbiota by voluntary exercise induces high physical activity in high-fat diet mice
by: Eri Oyanagi, et al.
Published: (2018)

Djulis Hull Improves Insulin Resistance and Modulates the Gut Microbiota in High-Fat Diet (HFD)-Induced Hyperglycaemia
by: Yu-Tang Tung, et al.
Published: (2021)

Effect of Berberine on Atherosclerosis and Gut Microbiota Modulation and Their Correlation in High-Fat Diet-Fed ApoE−/− Mice
by: Min Wu, et al.
Published: (2020)

UPLC-Q-TOF/MS based metabolomic profiling of serum and urine of hyperlipidemic rats induced by high fat diet
by: Qiong Wu, et al.
Published: (2014)

Date (<i>Phoenix dactylifera</i> L.) Fruits as a Potential Lipid-Lowering Therapy: Effect on High-Fat Diet and Triton-WR-1339-Induced Hyperlipidemic Rats
by: Eimad Dine Tariq Bouhlali, et al.
Published: (2023)

Effects of Pioglitazone on Increases in Visceral Fat Accumulation and Oxidative Stress in Spontaneously Hypertensive Hyperlipidemic Rats Fed a High-Fat Diet and Sucrose Solution
by: Ryo Saiki, et al.
Published: (2007)

Crosstalk between the Ketogenic Diet and Epilepsy: From the Perspective of Gut Microbiota
by: Yuying Fan, et al.
Published: (2019)

Potential benefits of metformin and pioglitazone combination therapy via gut microbiota and metabolites in high-fat diet-fed mice
by: Dongmei Wang, et al.
Published: (2022)

Direct CCL4 Inhibition Modulates Gut Microbiota, Reduces Circulating Trimethylamine N-Oxide, and Improves Glucose and Lipid Metabolism in High-Fat-Diet-Induced Diabetes Mellitus
by: Chang TT, et al.
Published: (2021)

Interactions Between Diets, Gut Microbiota and Host Metabolism
Published: (2020)

Antihyperlipidemic effect of Ficus dalhousiae miq. stem bark on Triton WR-1339 and high fat diet-induced hyperlipidemic rats
by: Surendran Surya, et al.
Published: (2017)

Changes in the Gut Microbiota May Affect the Clinical Efficacy of Oral Anticoagulants
by: Wenjun Chen, et al.
Published: (2022)

Crocin-I Protects Against High-Fat Diet-Induced Obesity via Modulation of Gut Microbiota and Intestinal Inflammation in Mice
by: Xiaoxian Xie, et al.
Published: (2022)

Fermented Rosa Roxburghii Tratt Juice Alleviates High-Fat Diet-Induced Hyperlipidemia in Rats by Modulating Gut Microbiota and Metabolites
by: Jiacheng Ji, et al.
Published: (2022)

High Fat Diet Alters Gut Microbiota and the Expression of Paneth Cell-Antimicrobial Peptides Preceding Changes of Circulating Inflammatory Cytokines
by: Xiulan Guo, et al.
Published: (2017)

Ramulus mori (Sangzhi) alkaloids regulates gut microbiota disorder and its metabolism profiles in obese mice induced by a high-fat diet
by: Dongdong Liu, et al.
Published: (2023)

The Role of Gut Microbiota in the Skeletal Muscle Development and Fat Deposition in Pigs
by: Qi Han, et al.
Published: (2022)

Butyrate Improves the Metabolic Disorder and Gut Microbiome Dysbiosis in Mice Induced by a High-Fat Diet
by: Feng Gao, et al.
Published: (2019)

Herbal Medicine, Gut Microbiota, and COVID-19
by: Ziqi Chen, et al.
Published: (2021)