Tetrahydrocurcumin Add‐On therapy to losartan in a rat model of diabetic nephropathy decreases blood pressure and markers of kidney injury

• Hauptverfasser: Mahyar Khazaeli (Verfasst von), Ane C. F. Nunes (Verfasst von), Yitong Zhao (Verfasst von), Mahziar Khazaali (Verfasst von), John Prudente (Verfasst von), Nosratola D. Vaziri (Verfasst von), Bhupinder Singh (Verfasst von), Wei Ling Lau (Verfasst von)
• Format: Buch
• Veröffentlicht: Wiley, 2023-04-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

Abstract Tetrahydrocurcumin (THC), a principal metabolite of curcumin, was tested in a rat model of type 2 diabetes mellitus. THC was administered via daily oral gavage with the lipid carrier polyenylphosphatidylcholine (PPC) as add‐on therapy to losartan (angiotensin receptor blocker) to examine ef...