Tetrahydrocurcumin Add‐On therapy to losartan in a rat model of diabetic nephropathy decreases blood pressure and markers of kidney injury

• Main Authors: Mahyar Khazaeli (Author), Ane C. F. Nunes (Author), Yitong Zhao (Author), Mahziar Khazaali (Author), John Prudente (Author), Nosratola D. Vaziri (Author), Bhupinder Singh (Author), Wei Ling Lau (Author)
• Format: Book
• Published: Wiley, 2023-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Tetrahydrocurcumin (THC), a principal metabolite of curcumin, was tested in a rat model of type 2 diabetes mellitus. THC was administered via daily oral gavage with the lipid carrier polyenylphosphatidylcholine (PPC) as add‐on therapy to losartan (angiotensin receptor blocker) to examine ef...