Betulinic Acid Attenuates Osteoarthritis via Limiting NLRP3 Inflammasome Activation to Decrease Interleukin-1β Maturation and Secretion

• Ngā kaituhi matua: Bo Liu (Author), Yanglin Wu (Author), Ting Liang (Author), Yunlong Zhou (Author), Guangdong Chen (Author), Jiaheng He (Author), Chenchen Ji (Author), Peixin Liu (Author), Chenhui Zhang (Author), Jun Lin (Author), Kece Shi (Author), Zongping Luo (Author), Naicheng Liu (Author), Xinlin Su (Author)
• Hōputu: Pukapuka
• I whakaputaina: Hindawi Limited, 2023-01-01T00:00:00Z.
• Ngā marau: article
• Urunga tuihono: Connect to this object online.

Introduction. Osteoarthritis (OA) is the most common degenerative joint disorder. Prior studies revealed that activation of NLRP3 inflammasome could promote the activation and secretion of interleukin-1β (IL-1β), which has an adverse effect on the progression of OA. Betulinic acid (BA) is a compound...