Betulinic Acid Attenuates Osteoarthritis via Limiting NLRP3 Inflammasome Activation to Decrease Interleukin-1β Maturation and Secretion

• मुख्य लेखकों: Bo Liu (लेखक), Yanglin Wu (लेखक), Ting Liang (लेखक), Yunlong Zhou (लेखक), Guangdong Chen (लेखक), Jiaheng He (लेखक), Chenchen Ji (लेखक), Peixin Liu (लेखक), Chenhui Zhang (लेखक), Jun Lin (लेखक), Kece Shi (लेखक), Zongping Luo (लेखक), Naicheng Liu (लेखक), Xinlin Su (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Hindawi Limited, 2023-01-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Introduction. Osteoarthritis (OA) is the most common degenerative joint disorder. Prior studies revealed that activation of NLRP3 inflammasome could promote the activation and secretion of interleukin-1β (IL-1β), which has an adverse effect on the progression of OA. Betulinic acid (BA) is a compound...