Antimicrobial Evaluation of Sulfonamides after Coupling with Thienopyrimidine Coplanar Structure

• المؤلفون الرئيسيون: Elshaymaa I. Elmongy (مؤلف), Wejdan S. Alanazi (مؤلف), Alhanouf I. Aldawsari (مؤلف), Asma A. Alfaouri (مؤلف), Reem Binsuwaidan (مؤلف)
• التنسيق: كتاب
• منشور في: MDPI AG, 2024-01-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

This work describes the design and synthesis of three series of hybrids of thienopyrimidines and sulfonamides. Dihydrofolate reductase enzyme was selected as a target for the in-silico screening of the synthesized thienopyrimidine-sulfonamide hybrid as an antibacterial, while squalene epoxidase was...