Morphine Antinociception Restored by Use of Methadone in the Morphine-Resistant Inflammatory Pain State

Morphine Antinociception Restored by Use of Methadone in the Morphine-Resistant Inflammatory Pain State

The antinociceptive effect of methadone in the morphine-resistant inflammatory pain state was described in the paw-withdrawal test using the complete Freund's adjuvant (CFA)-induced mouse inflammatory pain model. After intraplantar (i.pl.) injection of CFA, thermal hyperalgesia was observed in...

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Main Authors: Chizuko Watanabe (Author), Asami Komiyama (Author), Masaru Yoshizumi (Author), Shinobu Sakurada (Author), Hirokazu Mizoguchi (Author)
Format: Book
Published: Frontiers Media S.A., 2020-12-01T00:00:00Z.
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3rd Floor Main Library

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