Morphine Antinociception Restored by Use of Methadone in the Morphine-Resistant Inflammatory Pain State

• 主要な著者: Chizuko Watanabe (著者), Asami Komiyama (著者), Masaru Yoshizumi (著者), Shinobu Sakurada (著者), Hirokazu Mizoguchi (著者)
• フォーマット: 図書
• 出版事項: Frontiers Media S.A., 2020-12-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

The antinociceptive effect of methadone in the morphine-resistant inflammatory pain state was described in the paw-withdrawal test using the complete Freund's adjuvant (CFA)-induced mouse inflammatory pain model. After intraplantar (i.pl.) injection of CFA, thermal hyperalgesia was observed in...