Preparing anti-SARS-CoV-2 agent EIDD-2801 by a practical and scalable approach, and quick evaluation via machine learning

• Asıl Yazarlar: Zhen Qin (Yazar), Bin Dong (Yazar), Renbing Wang (Yazar), Dechun Huang (Yazar), Jubo Wang (Yazar), Xi Feng (Yazar), Jinlei Bian (Yazar), Zhiyu Li (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Elsevier, 2021-11-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

EIDD-2801 is an orally bioavailable prodrug, which will be applied for emergency use authorization from the U.S. Food and Drug Administration for the treatment of COVID-19. To investigate the optimal parameters, EIDD-2801 was optimized via a four-step synthesis with high purity of 99.9%. The hydroxy...