LEAP2 deletion in mice enhances ghrelin's actions as an orexigen and growth hormone secretagogue

• Главные авторы: Kripa Shankar (Автор), Nathan P. Metzger (Автор), Omprakash Singh (Автор), Bharath K. Mani (Автор), Sherri Osborne-Lawrence (Автор), Salil Varshney (Автор), Deepali Gupta (Автор), Sean B. Ogden (Автор), Shota Takemi (Автор), Corine P. Richard (Автор), Karabi Nandy (Автор), Chen Liu (Автор), Jeffrey M. Zigman (Автор)
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• Опубликовано: Elsevier, 2021-11-01T00:00:00Z.
• Предметы: article
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Objective: The hormone liver-expressed antimicrobial peptide-2 (LEAP2) is a recently identified antagonist and an inverse agonist of the growth hormone secretagogue receptor (GHSR). GHSR's other well-known endogenous ligand, acyl-ghrelin, increases food intake, body weight, and GH secretion and...