Harnessing Nanomedicine to Potentiate the Chemo-Immunotherapeutic Effects of Doxorubicin and Alendronate Co-Encapsulated in Pegylated Liposomes

• मुख्य लेखकों: Alberto Gabizon (लेखक), Hilary Shmeeda (लेखक), Benjamin Draper (लेखक), Ana Parente-Pereira (लेखक), John Maher (लेखक), Amaia Carrascal-Miniño (लेखक), Rafael T. M. de Rosales (लेखक), Ninh M. La-Beck (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2023-11-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Encapsulation of Doxorubicin (Dox), a potent cytotoxic agent and immunogenic cell death inducer, in pegylated (Stealth) liposomes, is well known to have major pharmacologic advantages over treatment with free Dox. Reformulation of alendronate (Ald), a potent amino-bisphosphonate, by encapsulation in...