Structural and Bioactivity Characterization of Filipin Derivatives from Engineered <i>Streptomyces filipinensis</i> Strains Reveals Clues for Reduced Haemolytic Action

• Main Authors: Eva G. Barreales (Author), Ángel Rumbero (Author), Tamara D. Payero (Author), Antonio de Pedro (Author), Ester Jambrina (Author), Jesús F. Aparicio (Author)
• Format: Book
• Published: MDPI AG, 2020-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The rise in the number of immunocompromised patients has led to an increased incidence of fungal infections, with high rates of morbidity and mortality. Furthermore, misuse of antifungals has boosted the number of resistant strains to these agents; thus, there is urgent need for new drugs against th...