Structural Characterization of Co-Crystals of Chlordiazepoxide with <i>p</i>-Aminobenzoic Acid and Lorazepam with Nicotinamide by DSC, X-ray Diffraction, FTIR and Raman Spectroscopy
The low water solubility of benzodiazepines seriously affects their bioavailability and, in consequence, their biological activity. Since co-crystallization has been found to be a promising way to modify undesirable properties in active pharmaceutical ingredients, the objective of this study was to...
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Format: | Book |
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MDPI AG,
2020-07-01T00:00:00Z.
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A1234.567 |
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