Mutations at opposite ends of the DIII/S4-S5 linker of sodium channel Na_V1.7 produce distinct pain disorders

• Główni autorzy: Tyrrell Lynda (Autor), Dib-Hajj Sulayman D (Autor), Cheng Xiaoyang (Autor), Wright Dowain A (Autor), Fischer Tanya Z (Autor), Waxman Stephen G (Autor)
• Format: Książka
• Wydane: SAGE Publishing, 2010-04-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Two groups of gain-of-function mutations in sodium channel Na_V1.7, which are expressed in dorsal root ganglion (DRG) neurons, produce two clinically-distinct pain syndromes - inherited erythromelalgia (IEM) and...