Mutations at opposite ends of the DIII/S4-S5 linker of sodium channel Na_V1.7 produce distinct pain disorders

• 主要な著者: Tyrrell Lynda (著者), Dib-Hajj Sulayman D (著者), Cheng Xiaoyang (著者), Wright Dowain A (著者), Fischer Tanya Z (著者), Waxman Stephen G (著者)
• フォーマット: 図書
• 出版事項: SAGE Publishing, 2010-04-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Two groups of gain-of-function mutations in sodium channel Na_V1.7, which are expressed in dorsal root ganglion (DRG) neurons, produce two clinically-distinct pain syndromes - inherited erythromelalgia (IEM) and...