Mesoporous Polydopamine Nanoparticles Attenuate Morphine Tolerance in Neuropathic Pain Rats by Inhibition of Oxidative Stress and Restoration of the Endogenous Antioxidant System

• Main Authors: Yaswanth Kuthati (Author), Prabhakar Busa (Author), Srikrishna Tummala (Author), Vaikar Navakanth Rao (Author), Venkata Naga Goutham Davuluri (Author), Yen-Peng Ho (Author), Chih-Shung Wong (Author)
• Format: Book
• Published: MDPI AG, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Oxidative stress resulting from reactive oxygen species (ROS) is known to play a key role in numerous neurological disorders, including neuropathic pain. Morphine is one of the commonly used opioids for pain management. However, long-term administration of morphine results in morphine antinociceptiv...